MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Retinoid and related drugs

Drug Safety update

October 2023: Isotretinoin (Roaccutane▼): introduction of new safety measures, including additional oversight of the initiation of treatment for patients under 18 years of age

April 2023: Isotretinoin (Roaccutane▼): new safety measures to be introduced in the coming months, including additional oversight on initiation of treatment for patients under 18 years

July 2021: Oral retinoid medicines (isotretinoin, alitretinoin, and acitretin): temporary monitoring advice during coronavirus (COVID-19) pandemic

August 2020: Isotretinoin (Roaccutane▼): reminder of important risks and precautions

 June 2019: Oral retinoid medicines▼: revised and simplified pregnancy prevention educational materials for healthcare professionals and women

 March 2019: Medicines with teratogenic potential: what is effective contraception and how often is pregnancy testing needed?

 October 2017: Isotretinoin (Roaccutane): rare reports of erectile dysfunction and decreased libido

 December 2014: Isotretinoin: risk of serious skin reactions.

 December 2014: Isotretinoin for severe acne: who should prescribe it

 December 2014: Isotretinoin (Roaccutane): reminder of possible risk of psychiatric disorders

 December 2014: Oral retinoids: pregnancy prevention—reminder of measures to minimise teratogenic risk

Topical retinoids are recommended for comedonal acne; they may initially cause redness of the skin and skin peeling. This usually settles with time.

Pregnancy - retinoids (systemic or topical) should be avoided.

Severe acne requires oral antibiotics and referral for consideration of isotretinoin for treatment failures.

Oral isotretinoin (Roaccutane®) is a toxic and teratogenic drug and can only be prescribed by Consultant Dermatologists.

Pack Price
45 gram
Pack Price
45 gram £16.43
Pack Price
30 capsule £21.94
Pack Price
30 capsule £15.00
56 capsule £25.09
Pack Price
56 capsule £25.20