MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Migraine

Drug Safety Update

June 2023: Non-steroidal anti-inflammatory drugs (NSAIDs): potential risks following prolonged use after 20 weeks of pregnancy

 January 2017: Intravenous N-acetylcysteine (NAC) for paracetamol overdose: reminder of authorised dose regimen; possible need for continued treatment with NAC. 

 December 2014: Treating paracetamol overdose with intravenous acetylcysteine: new guidance

NICE Guidance (see also drug specific links below)

 CG150 Headaches in over 12s: diagnosis and management, updated November 2015

 TA260 Botulinium toxin type A for the prevention of headaches in adults with chronic migraine, June 2012

Treatment of a migraine attack should be guided by response to previous treatment and the severity of the attacks. A simple analgesic such as aspirin, paracetamol (preferably in a soluble or dispersible form) or ibuprofen is often effective; concomitant antiemetic treatment may be required. If treatment with an analgesic is inadequate, an attack may be treated with a specific antimigraine compound such as a 5HT1-receptor agonist (‘triptan’).

Other drugs used in the treatment of migraine particularly prophylaxis against an attack include propranolol, topiramate, gabapentin and botulinum toxin.

See here for K&M CCG Management of Adults with Headaches and Migraines in Primary Care

Pack Price
100 tablet £2.92
100 tablet (10 x 10 tablets) £2.47
1000 tablet £21.56
16 tablet (2 x 8 tablets) £0.36
30 tablet (3 x 10 tablets) £1.07
32 tablet £0.67
Pack Price
100 capsule (10 x 10 capsules) £2.84
16 capsule £0.50
32 capsule £0.91
Pack Price
100 tablet (10 x 10 tablets) £20.15
24 tablet (4 x 6 tablets) £10.64
60 tablet £8.80
Pack Price
100 ml £4.71
500 ml
Pack Price
100 ml £3.78
1000 ml
200 ml £7.56
Pack Price
100 ml £4.32
500 ml £22.50
Pack Price
100 ml £4.54
1000 ml £45.40
200 ml £9.08
500 ml £22.70
Pack Price
10 suppository £11.95
Pack Price
10 suppository £34.60
Pack Price
10 suppository £62.31
Pack Price
10 suppository £41.27
Pack Price
10 vial
Pack Price
32 tablet (4 x 8 tablets) £1.26
100 tablet
Pack Price
10 suppository
Pack Price
10 suppository
Pack Price
24 tablet £1.42
48 tablet (4 x 12 tablets) £2.38
84 tablet £2.63
Pack Price
24 tablet £2.25
48 tablet (4 x 12 tablets) £1.00
84 tablet (7 x 12 tablets) £2.63
Pack Price
100 ml £2.16
150 ml £5.25
500 ml
Pack Price
42 tablet (3 x 14 tablets)
Pack Price
12 tablet £3.71
6 tablet £1.42
Pack Price
3 tablet
6 tablet £32.55
Pack Price
12 tablet
2 tablet
3 tablet £4.96
6 tablet
Pack Price
12 tablet
2 tablet
4 tablet
6 tablet £0.92
Pack Price
12 tablet
2 tablet
4 tablet
6 tablet £1.20
Pack Price
2 unit dose £14.16
Pack Price
2 pre-filled disposable injection £50.96
Pack Price
12 tablet (2 x 6 tablets) £28.86
6 tablet £23.62
Pack Price
6 tablet £48.53
Pack Price
6 tablet £17.68
Pack Price
6 tablet £19.06
Pack Price
6 unit dose £36.50
Pack Price
1 pre-filled disposable injection £386.50
Pack Price
2 tablet £25.80
8 tablet £103.20