MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Migraine

Drug Safety Update

 December 2014: Treating paracetamol overdose with intravenous acetylcysteine: new guidance

 January 2017: Intravenous N-acetylcysteine (NAC) for paracetamol overdose: reminder of authorised dose regimen; possible need for continued treatment with NAC. 

NICE guidance

 CG150 Headaches in over 12s: diagnosis and management, updated November 2015

 TA260 Botulinium toxin type A for the prevention of headaches in adults with chronic migraine, June 2012

Treatment of a migraine attack should be guided by response to previous treatment and the severity of the attacks. A simple analgesic such as aspirin, paracetamol (preferably in a soluble or dispersible form) or ibuprofen is often effective; concomitant antiemetic treatment may be required. If treatment with an analgesic is inadequate, an attack may be treated with a specific antimigraine compound such as a 5HT1-receptor agonist (‘triptan’).

Other drugs used in the treatment of migraine particularly prophylaxis against an attack include propranolol, topiramate, gabapentin and botulinum toxin .

Pack Price
100 tablet £2.13
100 tablet (10 x 10 tablets) £2.05
1000 tablet
16 tablet (2 x 8 tablets) £0.37
30 tablet (3 x 10 tablets) £0.70
32 tablet £0.46
Pack Price
100 capsule (10 x 10 capsules) £4.82
16 capsule £0.48
32 capsule £1.44
Pack Price
100 tablet (10 x 10 tablets) £7.50
24 tablet (4 x 6 tablets) £10.64
60 tablet £8.80
Pack Price
100 ml £1.76
500 ml
Pack Price
100 ml £1.93
1000 ml £16.70
200 ml £3.34
Pack Price
100 ml £2.68
500 ml £12.00
Pack Price
100 ml £1.63
1000 ml £12.38
200 ml £2.81
500 ml £7.00
Pack Price
10 suppository £11.95
Pack Price
10 suppository £12.39
Pack Price
10 suppository £22.01
Pack Price
10 suppository £40.79
Pack Price
10 vial £12.00
Pack Price
100 tablet
32 tablet (4 x 8 tablets) £1.26
Pack Price
10 suppository £20.54
Pack Price
10 suppository £39.48
Pack Price
24 tablet
48 tablet (4 x 12 tablets)
84 tablet £4.10
Pack Price
24 tablet £0.88
48 tablet (4 x 12 tablets)
84 tablet (7 x 12 tablets) £6.34
Pack Price
100 ml £1.97
150 ml £2.96
500 ml £9.85
Pack Price
42 tablet (3 x 14 tablets) £9.64
Pack Price
12 tablet
2 tablet
4 tablet
6 tablet £1.29
Pack Price
12 tablet
2 tablet
4 tablet
6 tablet £1.50
Pack Price
2 unit dose £14.16
Pack Price
2 pre-filled disposable injection £50.96
Pack Price
12 tablet (2 x 6 tablets) £21.00
6 tablet £5.71
Pack Price
6 tablet £4.78
Pack Price
6 tablet £9.92
Pack Price
6 tablet £13.41
Pack Price
6 unit dose £36.50
Pack Price
12 tablet £30.00
6 tablet £5.27
Pack Price
3 tablet
6 tablet £26.73
Pack Price
12 tablet
2 tablet
3 tablet £2.87
6 tablet