MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Migraine

Drug Safety Update

 December 2014: Treating paracetamol overdose with intravenous acetylcysteine: new guidance

 January 2017: Intravenous N-acetylcysteine (NAC) for paracetamol overdose: reminder of authorised dose regimen; possible need for continued treatment with NAC. 

NICE guidance

 CG150 Headaches in over 12s: diagnosis and management, updated November 2015

 TA260 Botulinium toxin type A for the prevention of headaches in adults with chronic migraine, June 2012

Treatment of a migraine attack should be guided by response to previous treatment and the severity of the attacks. A simple analgesic such as aspirin, paracetamol (preferably in a soluble or dispersible form) or ibuprofen is often effective; concomitant antiemetic treatment may be required. If treatment with an analgesic is inadequate, an attack may be treated with a specific antimigraine compound such as a 5HT1-receptor agonist (‘triptan’).

Other drugs used in the treatment of migraine particularly prophylaxis against an attack include propranolol, topiramate, gabapentin and botulinum toxin .

Pack Price
100 tablet £2.13
100 tablet (10 x 10 tablets) £2.05
1000 tablet
16 tablet (2 x 8 tablets) £0.39
30 tablet (3 x 10 tablets) £0.70
32 tablet £0.46
Pack Price
100 capsule (10 x 10 capsules) £4.68
16 capsule £0.48
32 capsule £1.76
Pack Price
100 tablet (10 x 10 tablets) £44.28
24 tablet (4 x 6 tablets) £10.64
60 tablet
Pack Price
100 ml £1.59
500 ml
Pack Price
100 ml £1.88
1000 ml £13.70
200 ml £3.18
Pack Price
100 ml £2.40
500 ml £12.00
Pack Price
100 ml £1.62
1000 ml £13.95
200 ml £2.74
500 ml £6.97
Pack Price
10 suppository £11.95
Pack Price
10 suppository £12.39
Pack Price
10 suppository £22.01
Pack Price
10 suppository £42.21
Pack Price
10 vial
Pack Price
100 tablet
32 tablet (4 x 8 tablets) £1.26
Pack Price
10 suppository £20.54
Pack Price
10 suppository £39.48
Pack Price
24 tablet
48 tablet (4 x 12 tablets)
84 tablet £3.85
Pack Price
24 tablet
48 tablet (4 x 12 tablets)
84 tablet (7 x 12 tablets) £7.50
Pack Price
100 ml £1.77
150 ml £2.38
500 ml £7.95
Pack Price
42 tablet (3 x 14 tablets) £9.64
Pack Price
12 tablet
2 tablet
4 tablet
6 tablet £1.50
Pack Price
12 tablet
2 tablet
4 tablet
6 tablet £1.63
Pack Price
2 unit dose £14.16
Pack Price
2 pre-filled disposable injection £50.96
Pack Price
12 tablet (2 x 6 tablets) £28.00
6 tablet £7.84
Pack Price
6 tablet £4.32
Pack Price
6 tablet £10.49
Pack Price
6 tablet £13.41
Pack Price
6 unit dose £36.50
Pack Price
12 tablet £30.00
6 tablet £6.22
Pack Price
3 tablet
6 tablet £26.73
Pack Price
12 tablet
2 tablet
3 tablet £3.77
6 tablet