Antiemetics and Antinauseants
Drug Safety Update
August 2012: Ondansetron (Zofran) important new intravenous dose restrictions for high doses used in the management of chemotherapy induced nausea and vomiting
August 2013: Ondansetron for intravenous use posology in patients aged 65 years and older - new advice on dilution and administration when being used for the management of chemotherapy induced nausea and vomiting
August 2013: Metoclopramide - risk of neurological side effects
May 2014: Domperidone - risk of cardiac side effects
December 2019: Domperidone for nausea and vomiting: lack of efficacy in children; reminder of contraindications in adults and adolescents
January 2020: Ondansetron: small increased risk of oral clefts following use in the first 12 weeks of pregnancy
July 2023: Hyoscine hydrobromide patches (Scopoderm 1.5mg Patch or Scopoderm TTS Patch): risk of anticholinergic side effects, including hyperthermia
First-line for PONV
Pack | Price |
---|---|
10 tablet | £9.50 |
30 tablet | £6.60 |
Pack | Price |
---|---|
10 tablet | £8.80 |
Pack | Price |
---|---|
10 tablet | £22.51 |
Pack | Price |
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10 tablet | £71.94 |
Pack | Price |
---|---|
50 ml | £23.16 |
Pack | Price |
---|---|
5 ampoule | £39.60 |
Pack | Price |
---|---|
5 ampoule |
Pack | Price |
---|---|
28 tablet (2 x 14 tablets) | £1.08 |
Pack | Price |
---|---|
150 ml | £13.24 |
Pack | Price |
---|---|
10 ampoule | £4.84 |
Useful for the treatment of vertigo
Pack | Price |
---|---|
28 tablet (2 x 14 tablets) | £1.71 |
84 tablet (6 x 14 tablets) | £5.13 |
Buccastem can be purchased OTC for nausea & vomiting in previously diagnosed migraine
Pack | Price |
---|---|
8 tablet | £4.01 |
Pack | Price |
---|---|
10 ampoule | £5.23 |
Effective in treating nausea and vomiting resulting from many underlying causes. Use second line for PONV.
Pack | Price |
---|---|
100 tablet (10 x 10 tablets) | £7.26 |
Pack | Price |
---|---|
5 ampoule | £10.70 |
Licensed for motion sickness also used off licence for hypersalivation
Releases 1mg hyoscine over 72hours
Pack | Price |
---|---|
2 patch | £12.87 |
Pack | Price |
---|---|
100 tablet (10 x 10 tablets) | £4.62 |
30 tablet (3 x 10 tablets) | £1.32 |
Pack | Price |
---|---|
200 ml | £49.32 |
Used in palliative care
Pack | Price |
---|---|
84 tablet (3 x 28 tablets) | £20.26 |
Pack | Price |
---|---|
10 ampoule | £20.13 |
Used for nausea & vomiting associated with cancer chemotherapy or palliative care.
Dexamethasone injection is usually prescribed in terms of dexamethasone base - see IV guide for more details.
Pack | Price |
---|---|
100 tablet | £9.80 |
50 tablet | £5.50 |
Pack | Price |
---|---|
10 ampoule | £14.21 |
Pack | Price |
---|---|
10 vial | £19.99 |
Pack | Price |
---|---|
10 ampoule | £39.99 |
Pack | Price |
---|---|
10 ampoule | £292.60 |