Antiemetics and Antinauseants
Drug Safety Update
August 2012: Ondansetron (Zofran) important new intravenous dose restrictions for high doses used in the management of chemotherapy induced nausea and vomiting
August 2013: Ondansetron for intravenous use posology in patients aged 65 years and older - new advice on dilution and administration when being used for the management of chemotherapy induced nausea and vomiting
August 2013: Metoclopramide - risk of neurological side effects
May 2014: Domperidone - risk of cardiac side effects
December 2019: Domperidone for nausea and vomiting: lack of efficacy in children; reminder of contraindications in adults and adolescents
January 2020: Ondansetron: small increased risk of oral clefts following use in the first 12 weeks of pregnancy
First-line for PONV
Pack | Price |
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10 tablet | £8.00 |
30 tablet | £2.46 |
Pack | Price |
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10 tablet | £1.92 |
Pack | Price |
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10 tablet | £43.48 |
Pack | Price |
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10 tablet | £85.43 |
Pack | Price |
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50 ml | £38.37 |
Pack | Price |
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5 ampoule | £40.17 |
Pack | Price |
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5 ampoule | £9.96 |
Pack | Price |
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28 tablet (2 x 14 tablets) | £1.21 |
Pack | Price |
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150 ml | £19.79 |
Pack | Price |
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10 ampoule | £3.60 |
Useful for the treatment of vertigo
Pack | Price |
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28 tablet (2 x 14 tablets) | £1.55 |
84 tablet (6 x 14 tablets) | £4.65 |
Buccastem can be purchased OTC for nausea & vomiting in previously diagnosed migraine
Pack | Price |
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8 tablet | £4.01 |
Pack | Price |
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100 ml | £3.34 |
Pack | Price |
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10 ampoule | £5.23 |
Effective in treating nausea and vomiting resulting from many underlying causes. Use second line for PONV.
Pack | Price |
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100 tablet (10 x 10 tablets) | £4.90 |
Pack | Price |
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5 ampoule | £11.35 |
Licensed for motion sickness also used off licence for hypersalivation
Releases 1mg hyoscine over 72hours
Pack | Price |
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2 patch | £12.87 |
Pack | Price |
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100 tablet (10 x 10 tablets) | £2.47 |
30 tablet (3 x 10 tablets) | £0.74 |
Pack | Price |
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200 ml | £24.85 |
Used in palliative care
Pack | Price |
---|---|
84 tablet (3 x 28 tablets) | £20.26 |
Pack | Price |
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10 ampoule |
Used for nausea & vomiting associated with cancer chemotherapy or palliative care.
Dexamethasone injection is usually prescribed in terms of dexamethasone base - see IV guide for more details.
Pack | Price |
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100 tablet | £9.90 |
50 tablet | £5.37 |
Pack | Price |
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10 ampoule | £23.99 |
Pack | Price |
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10 vial | £19.99 |
Pack | Price |
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10 ampoule | £47.21 |
Pack | Price |
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10 ampoule | £80.96 |