Important safety information
The CSM has warned that any degree of worsening of asthma may be related to the ingestion of NSAIDs, either prescribed or purchased over the counter
In osteoarthritis and soft-tissue disorders, many patients can achieve adequate control with paracetamol alone, (regular dosing may be required). NICE guidance recommends offering paracetamol and/or a topical NSAID before considering oral NSAIDs or COX-2 inhibitors for osteoarthritis. Only prescribe a NSAID if the benefits of treatment clearly outweigh the risks and a need for an anti-inflammatory agent is identified.
Choice of agent: NICE guidance recommends when offering treatment for osteoarthritis, use either a standard NSAID or a COX-2 inhibitor (not etoricoxib) as a first choice and always co-prescribe with a proton pump inhibitor.