These are the antimicrobials used within MTW NHS Trust and West Kent CCG, please refer to the appropriate Antimicrobial guidelines for guidance on the choice of antimicrobial for different indications.
Drug Safety Update
April 2023: Nitrofurantoin: reminder of the risks of pulmonary and hepatic adverse drug reactions
September 2014: Nitrofurantoin now contraindicated in most patients with eGFR of less than 45ml/1.73m2. However, a short course (3 to 7 days) may be used with caution in certain patients with an eGFR of 30 to 44 ml/min. Only prescribe to such patients to treat lower urinary tract infection with suspected or proven multi-drug resistant pathogens when the benefits of nitrofurantoin are considered to outweigh the risks of side effects. For more details please follow above link.
K&M Long-term Nitrofurantoin Safety Monitoring Guidance for Prescribers
K&M Nitrofurantoin Safety Patient Information Leaflet