Urinary frequency, enuresis and incontinence
Drug Safety Update
October 2015: Mirabegron (Betmiga▼): risk of severe hypertension and associated cerebrovascular and cardiac events
December 2014: Botulinum toxin products: rare but serious risks
NICE Guidance (also see drug-specific links below)
CG97: Lower urinary tract symptoms in men: management, June 2015
NG123: Urinary incontinence and pelvic organ prolapse in women: management, updated June 2019
CG148: Urinary incontinence in neurological disease: assessment and management, August 2012
TA290: Mirabegron for treating symptoms of overactive bladder, June 2013
Local Guidance
See here for local primary care guidance on the management of OAB in women
Not for use in the frail/elderly patient
| Pack | Price |
|---|---|
| 56 tablet (8 x 7 tablets) | £1.15 |
| 84 tablet (12 x 7 tablets) | £1.73 |
| Pack | Price |
|---|---|
| 56 tablet |
| Pack | Price |
|---|---|
| 56 tablet (8 x 7 tablets) | £1.28 |
| Pack | Price |
|---|---|
| 30 tablet | £13.77 |
| Pack | Price |
|---|---|
| 30 tablet | £27.54 |
| Pack | Price |
|---|---|
| 8 patch | £27.20 |
| Pack | Price |
|---|---|
| 150 ml | £372.00 |
| Pack | Price |
|---|---|
| 56 tablet (4 x 14 tablets) | £2.66 |
| Pack | Price |
|---|---|
| 56 tablet (4 x 14 tablets) | £2.90 |
| Pack | Price |
|---|---|
| 28 capsule (2 x 14 capsules) | £12.89 |
| Pack | Price |
|---|---|
| 28 tablet (2 x 14 tablets) | £25.48 |
| Pack | Price |
|---|---|
| 28 tablet (2 x 14 tablets) | £25.48 |
| Pack | Price |
|---|---|
| 28 tablet (4 x 7 tablets) | £25.78 |
| Pack | Price |
|---|---|
| 28 tablet (4 x 7 tablets) | £25.78 |
Higher dose is much more expensive than other antimuscarinics - use for existing patients only
| Pack | Price |
|---|---|
| 30 tablet (3 x 10 tablets) | £27.62 |
| Pack | Price |
|---|---|
| 30 tablet (3 x 10 tablets) | £35.91 |
Mirabegron is the first in a new class of drugs it is a beta-3-adrenoceptor agonist. It is reserved for those patients for whom antimuscarinics are contraindicated or clinically ineffective, or have unacceptable side effects.
| Pack | Price |
|---|---|
| 30 tablet (3 x 10 tablets) | £29.00 |
| Pack | Price |
|---|---|
| 30 tablet (3 x 10 tablets) | £29.00 |
Caution: Due to unit differences in the potency assay, unit doses for different brands of Botulinum A toxin are NOT interchangeable.
| Pack | Price |
|---|---|
| 1 vial | £77.50 |
| Pack | Price |
|---|---|
| 1 vial | £138.20 |
| Pack | Price |
|---|---|
| 1 vial | £72.00 |
| Pack | Price |
|---|---|
| 1 vial | £129.90 |