Drug Safety Update
March 2014: Orlistat may theoretically reduce the absorption of antiretroviral HIV medicines. Initiate orlistat treatment only after careful consideration of the possible impact on efficacy of antiretroviral HIV medicines. People who take antiretroviral HIV medicines should consult their doctor before taking non-prescription 60mg orlistat.
NICE guidance
CG43: Obesity prevention, December 2006 (updated March 2015)
CG189: Obesity: identification, assessment and management, November 2014
Lifestyle, dietary and exercise advice should be given initially before drug treatment is considered.
For information about Weygovy please see link here: Medicines Optimisation NHS Kent and Medway (icb.nhs.uk)
Kent and Medway ICB Position statement on Wegovy and GLP-1 receptor agonists (GLP-1 RAs) for weight loss
Formulary entries for Wegovy and Saxenda can be found here.