Drug Safety Update
April 2018: Obeticholic acid (Ocaliva▼): risk of serious liver injury in patients with pre-existing moderate or severe hepatic impairment; reminder to adjust dosing according to liver function monitoring
NICE Guidance (see drug specific link below)
Other drugs should be taken at least 1 hour before or 4 - 6 hours after colestyramine to reduce the possiblity of interference with absorption.
Obeticholic acid is available from a specialist centre only and should be initiated and supervised by an appropriate specialist.