Gastro-intestinal smooth muscle spasms
Drug Safety Update
December 2017: Eluxadoline : risk of pancreatitis; do not use in patients who have undergone cholecystectomy or in those with bilary disorders.
February 2017: Hyoscine butylbromide injection should be used with caution in patients with cardiac disease and is contraindicated in patients with tachycardia.
NICE Guidance (also see drug specific links below)
CG61: Irritable bowel syndrome in adults: diagnosis and management, February 2008 (updated April 2017)
Local Guidance
Please see here for K&M ICB Position Statement – GI Anti-spasmodics: Dicycloverine and Propantheline prescribing not supported
| Pack | Price |
|---|---|
| 100 capsule | £3.06 |
| Pack | Price |
|---|---|
| 60 capsule | £3.21 |
| Pack | Price |
|---|---|
| 20 tablet | |
| 40 tablet | |
| 56 tablet | £4.02 |
| Pack | Price |
|---|---|
| 10 ampoule | £4.08 |
This is prescribed in-line with NICE TA 471. It must be initiated in secondary care and stopped after 4 weeks if inadequate relief of symptoms. Cost is high compared to other treatments £88.20 for 1 month
| Pack | Price |
|---|---|
| 56 tablet |
| Pack | Price |
|---|---|
| 56 tablet |
| Pack | Price |
|---|---|
| 100 tablet | £212.26 |
| Pack | Price |
|---|---|
| 84 tablet (4 x 21 tablets) | £226.59 |