MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Gastro-intestinal smooth muscle spasms

Drug Safety Update

  February 2017: Hyoscine butylbromide injection should be used with caution in patients with cardiac disease and is contraindicated in patients with tachycardia. 

  December 2017: Eluxadoline : risk of pancreatitis; do not use in patients who have undergone cholecystectomy or in those with bilary disorders.

NICE Guidance (also see drug specific links below)

 CG61 Irritable bowel syndrome in adults: diagnosis and management February 2008 updated April 2017


Pack Price
100 tablet £3.66
15 tablet
60 tablet
90 tablet
Pack Price
12 capsule
25 capsule
84 capsule £7.04

This is prescribed in-line with NICE TA 471. It must be initiated in secondary care and stopped after 4 weeks if inadequate relief of symptoms. Cost is high compared to other treatments £88.20 for 1 month

Pack Price
56 tablet
Pack Price
56 tablet
Pack Price
1 ml
100 ml £11.26
200 ml
250 ml
300 ml
50 ml