Prostaglandin analogues and Prostamides
Drug Safety Update
July 2015: Latanoprost (Xalatan): increased reporting of eye irritation since reformulation
Prostaglandin analogues
These are used first line in the treatment for open angle glaucoma.
Prostaglandin analogues may cause an increase in brown iris pigment and patients should be counselled on possible changes in eye colour.
Adverse effects: initially they may cause conjunctival hyperaemia. This should not be painful and wears off as the eye becomes accustomed to it, (usually in about 4 weeks). It is more common with travaprost and bimatoprost. Following cataract surgery they can cause macular oedema.
First choice
| Pack | Price |
|---|---|
| 3 ml | £6.55 |
These drops are preservative-free for use as second line to the preservative-containing version of travoprost in cases of preservative allergy/toxicity
| Pack | Price |
|---|---|
| 30 unit dose (6 x 5 0.1ml unit doses) | £7.49 |
First choice
| Pack | Price |
|---|---|
| 3 ml | £13.95 |
| 8 ml (3 x 2.5ml bottles) | £39.68 |
| Pack | Price |
|---|---|
| 3 ml | £7.99 |
| Pack | Price |
|---|---|
| 3 ml | £11.71 |
| 9 ml (3 x 3ml bottles) | £35.13 |
| Pack | Price |
|---|---|
| 3 ml | £10.72 |
| Pack | Price |
|---|---|
| 3 ml | £2.00 |
These drops are preservative-free for use as second line to the preservative-containing version of latanoprost in cases of preservative allergy/toxicity
| Pack | Price |
|---|---|
| 30 unit dose (6 x 5 unit doses) | £8.49 |
| 90 unit dose (18 x 5 unit doses) | £25.47 |
| Pack | Price |
|---|---|
| 3 ml | £6.39 |
These drops are preservative-free for use as second line to the preservative-containing version of latanoprost & timolol in cases of preservative allergy/toxicity
| Pack | Price |
|---|---|
| 30 unit dose (6 x 5 unit doses) | £13.49 |
only use if preservative free preparation required
| Pack | Price |
|---|---|
| 30 unit dose (3 x 10 unit doses) | £14.50 |