MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Prostaglandin analogues and Prostamides

Drug Safety Update

 July 2015: Latanoprost (Xalatan): increased reporting of eye irritation since reformulation

Prostaglandin analogues
These are used first line in the treatment for open angle glaucoma.

Prostaglandin analogues may cause an increase in brown iris pigment and patients should be counselled on possible changes in eye colour.

Adverse effects: initially they may cause conjunctival hyperaemia. This should not be painful and wears off as the eye becomes accustomed to it, (usually in about 4 weeks). It is more common with travaprost and bimatoprost. Following cataract surgery they can cause macular oedema.

First choice

Pack Price
3 ml £2.79

First choice

Pack Price
3 ml £13.95
8 ml (3 x 2.5ml bottles) £39.68
Pack Price
3 ml £11.71
9 ml (3 x 3ml bottles) £35.13
Pack Price
3 ml £12.36
Pack Price
3 ml £14.16
9 ml (3 x 3ml bottles) £38.15
Pack Price
3 ml £3.60

Preservative-free unit dose formulation

Pack Price
30 unit dose (6 x 5 unit doses) £8.49
90 unit dose (18 x 5 unit doses) £25.47
Pack Price
3 ml £6.98

Preservative free single dose unit formulation 

Pack Price
30 unit dose (6 x 5 unit doses) £13.49

These drops are preservative free use second line to other prostaglandin eye drops

Pack Price
30 unit dose (3 x 10 unit doses) £12.20

only use if preservative free preparation required

Pack Price
30 unit dose (3 x 10 unit doses) £14.50