Prostaglandin analogues and Prostamides
Drug Safety Update
July 2015: Latanoprost (Xalatan): increased reporting of eye irritation since reformulation
Prostaglandin analogues
These are used first line in the treatment for open angle glaucoma.
Prostaglandin analogues may cause an increase in brown iris pigment and patients should be counselled on possible changes in eye colour.
Adverse effects: initially they may cause conjunctival hyperaemia. This should not be painful and wears off as the eye becomes accustomed to it, (usually in about 4 weeks). It is more common with travaprost and bimatoprost. Following cataract surgery they can cause macular oedema.
First choice
| Pack | Price |
|---|---|
| 3 ml | £13.95 |
| 8 ml (3 x 2.5ml bottles) | £39.68 |
| Pack | Price |
|---|---|
| 3 ml | £11.71 |
| 9 ml (3 x 3ml bottles) | £35.13 |
| Pack | Price |
|---|---|
| 3 ml | £12.36 |
| Pack | Price |
|---|---|
| 3 ml | £3.60 |
Preservative-free unit dose formulation
| Pack | Price |
|---|---|
| 30 unit dose (6 x 5 unit doses) | £8.49 |
| 90 unit dose (18 x 5 unit doses) | £25.47 |
| Pack | Price |
|---|---|
| 3 ml | £6.98 |
Preservative free single dose unit formulation
| Pack | Price |
|---|---|
| 30 unit dose (6 x 5 unit doses) | £13.49 |
These drops are preservative free use second line to other prostaglandin eye drops
| Pack | Price |
|---|---|
| 30 unit dose (3 x 10 unit doses) | £12.20 |
only use if preservative free preparation required
| Pack | Price |
|---|---|
| 30 unit dose (3 x 10 unit doses) | £14.50 |