MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Antidotes and chelators

Drug Safety Update

June 2020: Direct-acting oral anticoagulants (DOACs): reminder of bleeding risk, including availability of reversal agents

Idarucizumab binds specifically to dabigatran and its metabolites so reversing the anticoagulant effect

Pack Price
2 vial £2,400.00

Protamine sulfate is used to treat heparin and LMWH overdose

Pack Price
10 ampoule £49.55

Treatment of known or strongly suspected life-threatening digoxin toxicity associated with ventricular arrhythmias or bradycardia unresponsive to atropine. Used when measures beyond the withdrawal of digoxin and correction of any electrolyte abnormalities are considered necessary.

Pack Price
1 vial £750.00

Andexanet alfa is recommended as an option for reversing anticoagulation from rivaroxaban and apixaban in adults with life-threatening or uncontrolled bleeding if the bleed is in the GI tract

Pack Price
4 vial £11,100.00