Drug Safety Update
January 2014: Prasugrel increased risk of bleeding advice on loading dose
Aspirin and clopidogrel are also used in the management of patients with acute coronary syndromes. See NICE guidance and section Antiplatelet drugs.
Local Guidance
MTW Massive PE with thrombolysis protocol (update due 2020)
MTW use of in-hospital thrombolysis (update due 2020)
Alteplase is also approved for intrapleural use at MTW by a respiratory consultant for the management of pleural infection in adults (unlicensed indication and route) only when surgery/transfer to tertiary care is not an option. It is to be requested from pharmacy on an individual patient basis only for this indication.