Lipid regulating drugs
Drug Safety Update
 January 2008: Statin interactions and updated advice for atorvastatin
 February 2008: Statins - additional side effects including depression, sleep disturbance, memory loss, interstitial lung disease, and sexual dysfunction
 May 2010: Simvastatin increased risk of myopathy at high doses (80mg)
  December 2010: Fibrates first line treatment not recommended except for those with severe hypertriglyceridaemia
  January 2012: Statins risk of hyperglycaemia and diabetes
  August 2012: and October 2012 Updated advice on simvastatin interactions and co-prescribing with diltiazem or amlodipine
 May 2014: Statins: benefits and risks
NICE Guidance (also see drug-specific links below)
 CG181: Cardiovascular disease, risk assessment and reduction, including lipid modification, updated Sept 2016
 NICE flowchart: Familial hypercholesterolaemia overview, updated July 2018Â
Local guidance
Implementation Guidance for NICE TA 694: Bempedoic acid with ezetimibe for treating primary hypercholesterolemia or mixed dyslipedaemia
Colestyramine is an anion exchange resin and interferes with the absorption of other drugs. Other drugs should be taken at least 1 hour (ezetimibe 2 hours) before or 4-6 hours after taking colestyramine.
| Pack | Price |
|---|---|
| 28 tablet | £0.80 |
| 30 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £0.82 |
| Pack | Price |
|---|---|
| 28 tablet | £0.94 |
| Pack | Price |
|---|---|
| 28 tablet | £1.31 |
| Pack | Price |
|---|---|
| 100 tablet | |
| 14 tablet | |
| 28 tablet | £0.71 |
| 30 tablet | |
| 84 tablet | |
| 90 tablet |
| Pack | Price |
|---|---|
| 10 tablet | |
| 14 tablet | |
| 28 tablet | £0.93 |
| 30 tablet | |
| 84 tablet | |
| 90 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £0.99 |
| 30 tablet | |
| 90 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £1.33 |
| 30 tablet | |
| 90 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £0.95 |
| Pack | Price |
|---|---|
| 28 tablet | £1.09 |
| Pack | Price |
|---|---|
| 28 tablet | £1.29 |
| Pack | Price |
|---|---|
| 28 tablet | £0.92 |
| 30 tablet | |
| 90 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £1.04 |
| 30 tablet | |
| 98 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £1.27 |
| 30 tablet | |
| 98 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £1.70 |
Ezetimibe is only indicated for the treatment of primary heterozygous (familial and non-familial) hypercholesterolaemia where statins are contraindicated or not tolerated. Ezetimibe may be co-adminstered with a statin where response has not been adequate or increased doses of statin have not been tolerated.
| Pack | Price |
|---|---|
| 28 tablet | £1.39 |
| 30 tablet |
Bempedoic acid is recommended only in combination with ezetimbe. They may be prescribed as separate tablets or as the fixed dose combination.
| Pack | Price |
|---|---|
| 28 tablet (2 x 14 tablets) | £55.44 |
Bempedoic acid is recommended only in combination with ezetimbe. They may be prescribed as separate tablets or as the fixed dose combination.
| Pack | Price |
|---|---|
| 28 tablet | £55.44 |
To be prescribed according to NICE TA 733 (see link above).
| Pack | Price |
|---|---|
| 1 pre-filled disposable injection | £1,987.36 |
| Pack | Price |
|---|---|
| 100 tablet | £8.63 |
| Pack | Price |
|---|---|
| 28 tablet | |
| 30 tablet | £7.63 |
| Pack | Price |
|---|---|
| 60 capsule | |
| 90 capsule | £23.23 |
| Pack | Price |
|---|---|
| 28 tablet | £3.74 |
| 30 tablet |
| Pack | Price |
|---|---|
| 28 capsule | £2.73 |
| 30 capsule |
| Pack | Price |
|---|---|
| 28 capsule | £3.54 |
| 30 capsule |
| Pack | Price |
|---|---|
| 1 pre-filled disposable injection | £168.00 |
| 2 pre-filled disposable injection | £336.00 |
| Pack | Price |
|---|---|
| 1 pre-filled disposable injection | £168.00 |
| 2 pre-filled disposable injection | £336.00 |
| Pack | Price |
|---|---|
| 1 pre-filled disposable injection |
| Pack | Price |
|---|---|
| 2 pre-filled disposable injection | £340.20 |