Lipid regulating drugs
Drug Safety Update
January 2024: Omega-3-acid ethyl ester medicines (Omacor/Teromeg 1000mg capsules): dose-dependent increased risk of atrial fibrillation in patients with established cardiovascular diseases or cardiovascular risk factors
September 2023: Statins: very infrequent reports of myasthenia gravis
 May 2014: Statins: benefits and risks
October 2012: Simvastatin: evidence supporting recent advice on dose limitations with concomitant amlodipine or diltiazem
 August 2012: Simvastatin: updated advice on drug interactions - updated contraindications
 January 2012: Statins: risk of hyperglycaemia and diabetes
 December 2010: Fibrates: European Medicines Agency concludes first-line treatment is not recommendedÂ
 May 2010: Simvastatin: increased risk of myopathy at high doses (80mg)
 February 2008: Statins: class effects identified
 January 2008: Statin: interactions and updated advice for atorvastatin
NICE Guidance (also see drug-specific links below)
Summary of National Guidance for Lipid Management for Primary and Secondary Prevention of CVD
NG238: Cardiovascular disease, risk assessment and reduction, including lipid modification, December 2023
CG71: Familial hypercholesterolaemia: identification and management, August 2008 (updated October 2019)
Local guidance
Colestyramine is an anion exchange resin and interferes with the absorption of other drugs. Other drugs should be taken at least 1 hour (ezetimibe 2 hours) before or 4-6 hours after taking colestyramine.
| Pack | Price |
|---|---|
| 28 tablet | £0.65 |
| 30 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £1.22 |
| Pack | Price |
|---|---|
| 28 tablet | £0.86 |
| Pack | Price |
|---|---|
| 28 tablet | £1.85 |
| Pack | Price |
|---|---|
| 100 tablet | |
| 14 tablet | |
| 28 tablet | £0.86 |
| 30 tablet | |
| 84 tablet | |
| 90 tablet |
| Pack | Price |
|---|---|
| 10 tablet | |
| 14 tablet | |
| 28 tablet | £0.88 |
| 30 tablet | |
| 84 tablet | |
| 90 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £1.00 |
| 30 tablet | |
| 90 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £1.76 |
| 30 tablet | |
| 90 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £1.44 |
| Pack | Price |
|---|---|
| 28 tablet | £1.55 |
| Pack | Price |
|---|---|
| 28 tablet | £1.78 |
| Pack | Price |
|---|---|
| 28 tablet | £0.78 |
| 30 tablet | |
| 90 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £0.97 |
| 30 tablet | |
| 98 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £1.30 |
| 30 tablet | |
| 98 tablet |
| Pack | Price |
|---|---|
| 28 tablet | £1.58 |
Ezetimibe is only indicated for the treatment of primary heterozygous (familial and non-familial) hypercholesterolaemia where statins are contraindicated or not tolerated. Ezetimibe may be co-adminstered with a statin where response has not been adequate or increased doses of statin have not been tolerated.
| Pack | Price |
|---|---|
| 28 tablet | £6.40 |
| 30 tablet |
Bempedoic acid is recommended only in combination with ezetimbe. They may be prescribed as separate tablets or as the fixed dose combination.
| Pack | Price |
|---|---|
| 28 tablet (2 x 14 tablets) | £55.44 |
Bempedoic acid is recommended only in combination with ezetimbe. They may be prescribed as separate tablets or as the fixed dose combination.
| Pack | Price |
|---|---|
| 28 tablet | £55.44 |
To be prescribed according to NICE TA 733 and K&M ICB Position Statement (see here)
| Pack | Price |
|---|---|
| 1 pre-filled disposable injection | £1,987.36 |
To be prescribed according to NICE TA 805.
| Pack | Price |
|---|---|
| 120 capsule | £144.21 |
| Pack | Price |
|---|---|
| 100 tablet | £8.63 |
| Pack | Price |
|---|---|
| 28 tablet | |
| 30 tablet | £7.63 |
| Pack | Price |
|---|---|
| 60 capsule | |
| 90 capsule | £14.26 |
| Pack | Price |
|---|---|
| 28 tablet | £3.58 |
| 30 tablet |
| Pack | Price |
|---|---|
| 28 capsule | £2.84 |
| 30 capsule |
| Pack | Price |
|---|---|
| 28 capsule | £3.35 |
| 30 capsule |
| Pack | Price |
|---|---|
| 1 pre-filled disposable injection | £168.00 |
| 2 pre-filled disposable injection | £336.00 |
| Pack | Price |
|---|---|
| 1 pre-filled disposable injection | £168.00 |
| 2 pre-filled disposable injection | £336.00 |
| Pack | Price |
|---|---|
| 1 pre-filled disposable injection |
| Pack | Price |
|---|---|
| 2 pre-filled disposable injection | £340.20 |