MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Lipid regulating drugs

Drug Safety Update

  January 2008: Statin interactions and updated advice for atorvastatin

  February 2008: Statins - additional side effects including depression, sleep disturbance, memory loss, interstitial lung disease, and sexual dysfunction

 May 2010: Simvastatin increased risk of myopathy at high doses (80mg)

  December 2010: Fibrates first line treatment not recommended except for those with severe hypertriglyceridaemia

  January 2012: Statins risk of hyperglycaemia and diabetes

  August 2012: and  October 2012 Updated advice on simvastatin interactions and co-prescribing with diltiazem or amlodipine

 May 2014: Statins: benefits and risks

NICE Guidance (also see drug-specific links below)

 CG181: Cardiovascular disease, risk assessment and reduction, including lipid modification, updated Sept 2016

 NICE flowchart: Familial hypercholesterolaemia overview, updated July 2018 

Colestyramine is an anion exchange resin and interferes with the absorption of other drugs. Other drugs should be taken at least 1 hour (ezetimibe 2 hours) before or 4-6 hours after taking colestyramine.

Pack Price
28 tablet £1.15
30 tablet
Pack Price
28 tablet £1.13
Pack Price
28 tablet £1.30
Pack Price
28 tablet £1.74
Pack Price
100 tablet
14 tablet
28 tablet £1.01
30 tablet
84 tablet
90 tablet
Pack Price
10 tablet
14 tablet
28 tablet £1.41
30 tablet
84 tablet
90 tablet
Pack Price
28 tablet £1.50
30 tablet
90 tablet
Pack Price
28 tablet £2.10
30 tablet
90 tablet
Pack Price
28 tablet £1.24
Pack Price
28 tablet £1.46
Pack Price
28 tablet £1.84
Pack Price
28 tablet £1.45
30 tablet
90 tablet
Pack Price
28 tablet £1.69
30 tablet
98 tablet
Pack Price
28 tablet £2.02
30 tablet
98 tablet
Pack Price
28 tablet £2.53

Ezetimibe is only indicated for the treatment of primary heterozygous (familial and non-familial) hypercholesterolaemia where statins are contraindicated or not tolerated. Ezetimibe may be co-adminstered with a statin where response has not been adequate or increased doses of statin have not been tolerated.

Pack Price
28 tablet £2.37
30 tablet
Pack Price
100 tablet £8.63
Pack Price
28 tablet
30 tablet £7.63
Pack Price
60 capsule
90 capsule £23.23
Pack Price
28 tablet £4.59
30 tablet
Pack Price
28 capsule £3.47
30 capsule
Pack Price
28 capsule £4.64
30 capsule
Pack Price
1 pre-filled disposable injection £168.00
2 pre-filled disposable injection £336.00
Pack Price
1 pre-filled disposable injection £168.00
2 pre-filled disposable injection £336.00