MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Lipid regulating drugs

Drug Safety Update

January 2024: Omega-3-acid ethyl ester medicines (Omacor/Teromeg 1000mg capsules): dose-dependent increased risk of atrial fibrillation in patients with established cardiovascular diseases or cardiovascular risk factors

September 2023: Statins: very infrequent reports of myasthenia gravis

 May 2014: Statins: benefits and risks

October 2012: Simvastatin: evidence supporting recent advice on dose limitations with concomitant amlodipine or diltiazem

 August 2012: Simvastatin: updated advice on drug interactions - updated contraindications

 January 2012: Statins: risk of hyperglycaemia and diabetes

 December 2010: Fibrates: European Medicines Agency concludes first-line treatment is not recommended 

 May 2010: Simvastatin: increased risk of myopathy at high doses (80mg)

  February 2008: Statins: class effects identified

  January 2008: Statin: interactions and updated advice for atorvastatin

NICE Guidance (also see drug-specific links below)

Summary of National Guidance for Lipid Management for Primary and Secondary Prevention of CVD

NG238: Cardiovascular disease, risk assessment and reduction, including lipid modification, December 2023

CG71: Familial hypercholesterolaemia: identification and management, August 2008 (updated October 2019)

Colestyramine is an anion exchange resin and interferes with the absorption of other drugs. Other drugs should be taken at least 1 hour (ezetimibe 2 hours) before or 4-6 hours after taking colestyramine.

Pack Price
28 tablet £0.66
30 tablet
Pack Price
28 tablet £0.74
Pack Price
28 tablet £0.84
Pack Price
28 tablet £1.87
Pack Price
100 tablet
14 tablet
28 tablet £1.29
30 tablet
84 tablet
90 tablet
Pack Price
10 tablet
14 tablet
28 tablet £1.26
30 tablet
84 tablet
90 tablet
Pack Price
28 tablet £1.68
30 tablet
90 tablet
Pack Price
28 tablet £3.15
30 tablet
90 tablet
Pack Price
28 tablet £1.48
Pack Price
28 tablet £1.62
Pack Price
28 tablet £1.91
Pack Price
28 tablet £0.87
30 tablet
90 tablet
Pack Price
28 tablet £1.18
30 tablet
98 tablet
Pack Price
28 tablet £1.84
30 tablet
98 tablet
Pack Price
28 tablet £1.52

Ezetimibe is only indicated for the treatment of primary heterozygous (familial and non-familial) hypercholesterolaemia where statins are contraindicated or not tolerated. Ezetimibe may be co-adminstered with a statin where response has not been adequate or increased doses of statin have not been tolerated.

Pack Price
28 tablet £3.17
30 tablet

Bempedoic acid is recommended only in combination with ezetimbe. They may be prescribed as separate tablets or as the fixed dose combination.

Pack Price
28 tablet (2 x 14 tablets) £55.44

Bempedoic acid is recommended only in combination with ezetimbe. They may be prescribed as separate tablets or as the fixed dose combination.

Pack Price
28 tablet £55.44

To be prescribed according to NICE TA 733 and K&M ICB Position Statement (see here)

Pack Price
1 pre-filled disposable injection £1,987.00

To be prescribed according to NICE TA 805.

Pack Price
120 capsule £144.21
Pack Price
100 tablet £8.63
Pack Price
28 tablet
30 tablet £7.63
Pack Price
60 capsule
90 capsule £21.18
Pack Price
28 tablet £3.08
30 tablet
Pack Price
28 capsule £2.69
30 capsule
Pack Price
28 capsule £3.08
30 capsule
Pack Price
1 pre-filled disposable injection £168.00
2 pre-filled disposable injection £336.00
Pack Price
1 pre-filled disposable injection £168.00
2 pre-filled disposable injection £336.00