MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Bisphosphonates

Drug Safety Update

 December 2015: Bisphosphonates and very rare reports of osteonecrosis of the external auditory canal. See also see BNF for safety guidance.

 June 2011: Bisphosphonates and atypical femoral fractures. See also see BNF for safety guidance.

 April 2010: Intravenous zoledronic acid: adverse effects on renal function

 November 2009: Bisphosphonates and osteonecrosis of the jaw. See also see BNF for safety guidance.

 July 2008: Bisphosphonates and atrial fibrillation

National guidance

 TA464 Bisphosphonates for treating osteoporosis, updated February 2018

 NICE Osteoporosis pathway, February 2018

 National Osteoporosis Guideline Group (NOGG) Clinical guideline for the prevention and treatment of osteoporosis, updated July 2018