MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Paracetamol toxicity

 December 2014: Treating paracetamol overdose with intravenous acetylcysteine: new guidance.

 July 2016: N-acetylcysteine: risk of false-low biochemistry test results due to interference with Siemens assays.

 January 2017: Intravenous N-acetylcysteine (NAC) for paracetamol overdose: reminder of authorised dose regimen; possible need for continued treatment with NAC.

 Royal College of Emergency Medicine (RCEM) Paracetamol overdose new guidance on the use of intravenous acetylcysteine.

A new weight-based dosing table and a technical information leaflet to help calculate the dose of acetylcysteine infusions to minimise the risk of dosing errors are available to download