MTW NHS Trust West Kent CCG

Drug Status Key

  • Preferred
  • Second Line
  • Third Line
  • Specialist Initiation
  • Hospital Only
  • Not Approved for Formulary

Opioid toxicity

Important safety information

Doses used in acute opioid over-dosage may not be appropriate for the management of opioid -induced respiratory depression and sedation in those receiving palliative care and in chronic opioid use.

 CG52: Drug misuse in over 16s: opioid detoxification, July 2007

Naloxone will immediately reverse opioid-induced respiratory depression but the dose may have to be repeated because of the short duration of action of naloxone; however naloxone will also antagonise the analgesic effect.

Pack Price
10 ampoule (2 x 5 x 1ml ampoules) £40.50